By K. Schimrigk
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Additional info for Abstracts of the 65th congress of the German Society of Neurology
14 patients suffered from a brainstem TIA, 34 patients had a completed brainstem strake and 8 patients an infarction in the area of the posterior cerebral artery (PCA). 6 + 3,1 month. During the followup a neurological examination including the assessment of the Barthel-index of daily life activity as weil as a special designed VBI-score were performed at the acute state and at tree month intervals. The follow-up examinations included an cw-Doppler sonography of the extracranial arteries and the Doppler-C0 2 -Test in the basilar artery.
Color coded References: (1) Büdingen HJ, Von Reutern GM, Freund HJ (1976) The selective examination of the neck arteries by directional Doppler sonography. Arch Psychiatr Nervenkr 222:177-190 (2) Aaslid R, Markwalder TM, Nornes H (1982) Noninvasive transcranial Doppler Ultrasound recording of flow velocity in basal cerebral arteries. J Neurosurg 57:769-774 (3) Delcker A, Diener HC (1992) Color coded duplex sonography in the evaluation of vertebral arteries. Imaging 59:16-21 S30 59 60 COLOR DOPPLER IMAGING IN PATIENTS WITH DISSECTIONS TCD-MONITORING OF THERAPEUTIC CAROTID OCCLUSIONS A.
The arginine is highly conserved between species during evolution, indicating functional importance. The mutationalso removes a Sfa NI site on DNA Ievel and thus enables us to identify the mutation easily by Sfa NI digestion of a PCR amplified fragment encompassing the mutation. The applied assay is easy to use in clinical diagnostics and can be scaled down to the non-invasive analysis of mtDNA obtained from plugged hairs of patients and relatives. References: I. Wallace DC (1992) Mitochondrial Genetics: A Paradigm forAging and Degenerative Disease?